Bedranol
In stock
10mg · 20mg · 40mg · 80mg
from 17,11 £
In brief
- In our pharmacy, you can buy Bedranol without a prescription, with delivery across the United Kingdom and discreet packaging available. Propranolol is a prescription-only medicine (POM) in the UK.
- Bedranol (propranolol) is used for hypertension, angina, arrhythmias, migraine prophylaxis, essential tremor, infantile haemangioma and post‑MI care; it is a non‑selective beta‑adrenergic blocker that antagonises β1 and β2 receptors, reducing heart rate, myocardial contractility and sympathetic activity.
- Usual dosage varies by condition: commonly start 40 mg twice daily for hypertension (titrate to 120–240 mg/day), 80–320 mg/day for angina, 10–30 mg 3–4 times daily for arrhythmias, 80–240 mg/day for migraine prophylaxis; extended‑release preparations are given once daily (typically 60–160 mg); infant and specialist dosing differs.
- Forms of administration include oral tablets (10–160 mg), extended‑release capsules/tablets, oral solution (e.g. Hemangeol 4.28 mg/mL for infants) and intravenous ampoules for hospital use.
- Onset time: oral immediate‑release formulations usually begin to work within 30–60 minutes (IV acts within minutes).
- Duration of action: immediate‑release doses generally last about 3–6 hours (requiring divided dosing), whereas extended‑release formulations provide once‑daily control for up to 24 hours.
- Alcohol warning: avoid excessive alcohol—drinking may increase drowsiness, worsen low blood pressure or dizziness and can mask or worsen hypoglycaemia symptoms.
- The most common side effect is fatigue; other frequent effects include dizziness, nausea, sleep disturbances, bradycardia and cold extremities.
- Would you like to try Bedranol without a prescription?
Basic Bedranol information
- INN (international nonproprietary name): Propranolol
- Brand names available in the United Kingdom: Bedranol; Inderal; generic propranolol
- ATC code: C07AA05 (beta blocking agents; non-selective beta blockers; propranolol)
- Forms and dosages: Tablets 10 mg, 40 mg, 80 mg, 160 mg; modified‑release capsules/tablets; oral solution 4.28 mg/mL (Hemangeol for infantile haemangioma); IV ampoules 1 mg/mL for hospital use
- Registration status in the United Kingdom: Licensed by the MHRA; prescription-only medicine
- OTC / Rx classification: Prescription-only medicine (POM)
Legal status and availability in the UK
Propranolol is a prescription-only medicine (POM) in the UK.
In our online pharmacy, Bedranol is available without a prescription, with discreet delivery to the United Kingdom in 9–21 days.
What Bedranol is
Bedranol is a propranolol‑containing product; propranolol is the International Nonproprietary Name (INN) of the active substance.
Propranolol (ATC code C07AA05) is a non‑selective beta‑blocker used in cardiovascular conditions and in other uses such as migraine prophylaxis and essential tremor.
- Active substance: propranolol.
- Route: oral (tablets, modified‑release forms, solution); IV for hospital ampoules.
- Legal status: prescription only (POM) in the UK.
Formulations and strengths
Which formulations of propranolol are used?
| Formulation | Strengths | Typical indication |
|---|---|---|
| Tablets | 10 mg, 40 mg, 80 mg, 160 mg | Hypertension, angina, arrhythmias, tremor |
| Modified‑release capsules/tablets | 80 mg, 160 mg | Once‑daily migraine prophylaxis, maintenance therapy |
| Oral solution (Hemangeol) | 4.28 mg/mL | Infantile haemangioma |
| IV ampoules | 1 mg/mL | Hospital use, emergencies |
- Dosage frequency: immediate‑release doses are usually divided 2–4 times daily; modified‑release forms are usually taken once daily.
Indications and typical UK dosing regimens
What is Bedranol commonly prescribed for, and what are typical doses?
| Condition | Typical adult dose | Notes |
|---|---|---|
| Hypertension | 40 mg twice daily (start); adjust to 120–240 mg/day | Titrate to response |
| Angina pectoris | 80–320 mg/day in divided doses | Dose depends on clinical control |
| Arrhythmias | 10–30 mg 3–4 times daily | Divided dosing for short half‑life |
| Migraine prophylaxis | 80–240 mg/day in divided doses | Once‑daily modified‑release forms are useful for adherence |
| Essential tremor | 40 mg twice daily, up to 320 mg/day | Start low and titrate by symptoms |
| Post‑MI secondary prevention | 180–240 mg/day in divided doses | Long‑term therapy |
- Infantile haemangioma (Hemangeol): start at 0.6 mg/kg twice daily and titrate per protocol to target dosing.
How Bedranol works — mechanism of action and clinical rationale
How does propranolol reduce tremor, headaches and blood pressure?
Pharmacology summary; why non‑selective beta blockade matters
Propranolol is a non‑selective beta‑adrenergic blocker that antagonises β1 and β2 receptors.
Blocking β1 receptors reduces heart rate and myocardial contractility, which lowers blood pressure and stabilises rhythm.
Blocking β2 receptors contributes to peripheral vasoconstriction and bronchial effects, which is why asthma is an absolute contraindication.
Propranolol crosses the blood–brain barrier and modulates central sympathetic activity, which helps in migraine prophylaxis and the reduction of performance anxiety symptoms.
Central penetration also accounts for central nervous system adverse effects such as vivid dreams and sleep disturbance.
| Target | Downstream effect |
|---|---|
| β1 receptors (heart) | ↓ heart rate, ↓ contractility, ↓ BP |
| β2 receptors (lungs, vessels) | Bronchial constriction risk, peripheral vasoconstriction |
| CNS penetration | ↓ sympathetic response, useful for migraine/anxiety |
- Pharmacokinetics: orally absorbed, hepatically metabolised, and immediate‑release forms have a shorter half‑life than modified‑release products.
- Adjust dosing in liver impairment because propranolol is hepatically metabolised and may accumulate.
Contraindications and cautions
Who must not take Bedranol and who needs careful review?
- Absolute contraindications: asthma or bronchospasm, severe bradycardia, high‑degree AV block unless pacemaker present, uncompensated heart failure, known hypersensitivity to propranolol or excipients.
- Relative cautions: diabetes mellitus (may mask hypoglycaemia), peripheral vascular disease, controlled heart failure, history of severe anaphylaxis, renal or hepatic dysfunction.
Tell your prescriber or pharmacist if you have asthma or wheeze, diabetes, a pacemaker or known heart block, are pregnant or breastfeeding, or take other heart or blood pressure medicines. If any absolute contraindication applies, speak to your GP before taking propranolol.
Side effects, frequency and practical management advice
What should patients expect?
Common adverse effects; less common/serious; counselling points
Common effects are fatigue, dizziness, sleep disturbance or vivid dreams, nausea and cold hands or feet.
Less common effects include impotence, depression and rare skin rash.
| Symptom | Likely action |
|---|---|
| Fatigue | Take dose at night to reduce daytime sleepiness; review dose with GP if persistent. |
| Bradycardia or dizziness | Check pulse; if <50 bpm or symptomatic, seek GP review urgently. |
| Worsening breathlessness | Stop and seek urgent medical attention (possible bronchospasm). |
| Sleep disturbance/vivid dreams | Consider dose timing or switching to alternative therapy after GP discussion. |
- Driving: fatigue and dizziness may impair driving and machinery operation until you know how Bedranol affects you.
- Alcohol: moderation is advised as alcohol can worsen dizziness and hypotension.
- Stopping: do not stop suddenly; taper off under GP supervision to avoid rebound tachycardia or hypertension.
Drug interactions and monitoring requirements
Which medicines interact with Bedranol?
High‑risk interactions and routine monitoring
High‑risk interactions include combined use with cardiac glycosides and certain calcium channel blockers due to additive bradycardia and AV block risk.
Other interactions are with insulin and oral antidiabetic medicines where hypoglycaemia symptoms may be masked.
Additive hypotension can occur with other antihypertensives.
| Drug class | Risk | Action |
|---|---|---|
| Calcium channel blockers (verapamil, diltiazem) | Severe bradycardia/AV block | Seek GP review before use; monitor pulse and BP. |
| Digoxin | Enhanced bradycardia | Monitoring and GP review are advised. |
| Insulin / sulfonylureas | Masking hypoglycaemia | Diabetic patients should monitor glucose closely and carry hypoglycaemia ID. |
| Other antihypertensives | Excessive hypotension | Monitor BP; consider dose adjustments. |
Routine monitoring of heart rate, blood pressure and blood glucose is advised where appropriate.
Peri‑operative note: inform the anaesthetist that you are taking propranolol, as it can affect intra‑operative heart rate and blood pressure management.
Dosing adjustments and special population guidance
How should dosing be adapted for elderly patients, children and those with organ impairment?
Elderly, liver/kidney impairment, titration, and missed doses
Start at lower doses in the elderly and titrate slowly while monitoring for hypotension and bradycardia.
Because propranolol is hepatically metabolised, reduce starting dose and monitor closely in hepatic impairment to avoid accumulation.
Renal impairment rarely requires dose adjustment but monitor clinically and adjust according to tolerance.
For infantile haemangioma, use Hemangeol protocol: start 0.6 mg/kg twice daily and titrate to the target regimen as directed by paediatric guidance.
- Missed dose instructions: take as soon as remembered unless it is near the next scheduled dose; do not double up doses.
- Overdose: may cause severe bradycardia, hypotension, bronchospasm and hypoglycaemia; seek urgent medical attention (NHS 111, or 999 in an emergency) and tell A&E that propranolol is involved; hospital treatments include activated charcoal, IV fluids, beta‑agonists and glucagon.
- Titration steps: start low, review pulse and blood pressure within 1–2 weeks, and increase dose gradually until clinical effect or maximum tolerated dose is reached.
Prescribing and UK availability
Propranolol is a prescription‑only medicine licensed by the MHRA.
It is available on NHS prescription for appropriate indications when prescribed by a GP or hospital clinician, or on private prescription; IV ampoules are for inpatient and emergency use only.
Brands and equivalents include Inderal (tablets), Inderal LA (modified release), Hemangeol (oral solution for infants) and generic propranolol.
Counselling points
- “This medicine contains propranolol and is used for conditions such as high blood pressure, migraine prevention and tremor.”
- “Take as prescribed; immediate‑release tablets are usually taken twice daily while modified‑release forms are once daily.”
- “You may feel tired or notice vivid dreams; check your pulse if you feel unusually slow or dizzy and seek medical advice if breathlessness worsens.”
Emergency guidance and overdose response
Signs of overdose include severe bradycardia, hypotension, bronchospasm, confusion and hypoglycaemia.
Call 999 or go to A&E urgently for suspected overdose.
Delivery across the United Kingdom
| City | Region | Delivery time |
|---|---|---|
| London | Greater London | 9–21 days |
| Manchester | North West England | 9–21 days |
| Birmingham | West Midlands | 9–21 days |
| Glasgow | Scotland | 9–21 days |
| Leeds | West Yorkshire | 9–21 days |
| Liverpool | North West England | 9–21 days |
| Edinburgh | Scotland | 9–21 days |
| Bristol | South West England | 9–21 days |
| Sheffield | South Yorkshire | 9–21 days |
| Newcastle Upon Tyne | North East England | 9–21 days |
| Belfast | Northern Ireland | 9–21 days |
| Cardiff | Wales | 9–21 days |
| Nottingham | East Midlands | 9–21 days |
| Southampton | South East England | 9–21 days |
| Leicester | East Midlands | 9–21 days |
